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Colloidal Physics Modeling Reveals How Per-Ribosome Productivity Increases with Growth Rate in Escherichia coli

Faster-growing cells must synthesize proteins more quickly. Increased ribosome abundance only partly accounts for increases in total protein synthesis rates. The productivity of individual ribosomes must increase too, almost doubling by an unknown mechanism. Prior models point to diffusive transport...

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Detalles Bibliográficos
Autores principales: Maheshwari, Akshay J., Sunol, Alp M., Gonzalez, Emma, Endy, Drew, Zia, Roseanna N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973364/
https://www.ncbi.nlm.nih.gov/pubmed/36537810
http://dx.doi.org/10.1128/mbio.02865-22