Landscape of Genetic Alterations Underlying Hallmark Signature Changes in Cancer Reveals TP53 Aneuploidy–driven Metabolic Reprogramming

The hallmark signatures based on gene expression capture core cancer processes. Through a pan-cancer analysis, we describe the overview of hallmark signatures across tumor types/subtypes and reveal significant relationships between these signatures and genetic alterations. TP53 mutation exerts diver...

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Detalles Bibliográficos
Autores principales: McClure, Marni B., Kogure, Yasunori, Ansari-Pour, Naser, Saito, Yuki, Chao, Hann-Hsiang, Shepherd, Jonathan, Tabata, Mariko, Olopade, Olufunmilayo I., Wedge, David C., Hoadley, Katherine A., Perou, Charles M., Kataoka, Keisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973382/
https://www.ncbi.nlm.nih.gov/pubmed/36860655
http://dx.doi.org/10.1158/2767-9764.CRC-22-0073

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