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Smoking-associated Downregulation of FILIP1L Enhances Lung Adenocarcinoma Progression Through Mucin Production, Inflammation, and Fibrosis

Lung adenocarcinoma (LUAD) is the major subtype in lung cancer, and cigarette smoking is essentially linked to its pathogenesis. We show that downregulation of Filamin A interacting protein 1-like (FILIP1L) is a driver of LUAD progression. Cigarette smoking causes its downregulation by promoter meth...

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Detalles Bibliográficos
Autores principales:	Kwon, Mijung, Rubio, Genesaret, Wang, Haitao, Riedlinger, Gregory, Adem, Asha, Zhong, Hua, Slegowski, Daniel, Post-Zwicker, Louisa, Chidananda, Anshruta, Schrump, David S., Pine, Sharon R., Libutti, Steven K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973389/ https://www.ncbi.nlm.nih.gov/pubmed/36860703 http://dx.doi.org/10.1158/2767-9764.CRC-22-0233

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