MYC Inhibition Halts Metastatic Breast Cancer Progression by Blocking Growth, Invasion, and Seeding

MYC's role in promoting tumorigenesis is beyond doubt, but its function in the metastatic process is still controversial. Omomyc is a MYC dominant negative that has shown potent antitumor activity in multiple cancer cell lines and mouse models, regardless of their tissue of origin or driver mut...

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Detalles Bibliográficos
Autores principales: Massó-Vallés, Daniel, Beaulieu, Marie-Eve, Jauset, Toni, Giuntini, Fabio, Zacarías-Fluck, Mariano F., Foradada, Laia, Martínez-Martín, Sandra, Serrano, Erika, Martín-Fernández, Génesis, Casacuberta-Serra, Sílvia, Castillo Cano, Virginia, Kaur, Jastrinjan, López-Estévez, Sergio, Morcillo, Miguel Ángel, Alzrigat, Mohammad, Mahmoud, Loay, Luque-García, Antonio, Escorihuela, Marta, Guzman, Marta, Arribas, Joaquín, Serra, Violeta, Larsson, Lars-Gunnar, Whitfield, Jonathan R., Soucek, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973395/
https://www.ncbi.nlm.nih.gov/pubmed/36860495
http://dx.doi.org/10.1158/2767-9764.CRC-21-0103

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