Cargando…

Enhancing regulatory T-cell function via inhibition of high mobility group box 1 protein signaling in immune thrombocytopenia

Primary immune thrombocytopenia (ITP) is the most common acquired autoimmune bleeding disorder. Abnormally increased levels of High Mobility Group Box 1 (HMGB1) protein associate with thrombocytopenia and therapeutic outcome in ITP. Previous studies proposed that a natural inhibitor of HMGB1, 18β-gl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Haoyi, Yu, Tianshu, An, Ning, Sun, Yunqi, Xu, Pengcheng, Han, Panpan, Zhao, Yajing, Wang, Lingjun, Ni, Xiaofei, Li, Yubin, Li, Guosheng, Liu, Yanfeng, Peng, Jun, Hou, Ming, Hou, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Fondazione Ferrata Storti 2022
Materias:	Article - Platelet Biology & its Disorders
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973480/ https://www.ncbi.nlm.nih.gov/pubmed/36263841 http://dx.doi.org/10.3324/haematol.2022.281557

Ejemplares similares

Low-dose decitabine modulates T-cell homeostasis and restores immune tolerance in immune thrombocytopenia
por: Han, Panpan, et al.
Publicado: (2021)

Antiplatelet antibody predicts platelet desialylation and apoptosis in immune thrombocytopenia
por: Zheng, Shiying Silvia, et al.
Publicado: (2022)

Adolescents and young adults with newly diagnosed primary immune thrombocytopenia
por: Schifferli, Alexandra, et al.
Publicado: (2023)

Targeting a thrombopoietin-independent strategy in the discovery of a novel inducer of megakaryocytopoiesis, DMAG, for the treatment of thrombocytopenia
por: Wang, Long, et al.
Publicado: (2022)

Exome sequencing in 116 patients with inherited thrombocytopenia that remained of unknown origin after systematic phenotype-driven diagnostic workup
por: Marconi, Caterina, et al.
Publicado: (2022)

Defective binding of ETS1 and STAT4 due to a mutation in the promoter region of THPO as a novel mechanism of congenital amegakaryocytic thrombocytopenia
por: Capaci, Valeria, et al.
Publicado: (2022)

Establishment of a Bernard-Soulier syndrome model in zebrafish
por: Lin, Qing, et al.
Publicado: (2021)

Abnormalities of bone marrow B cells and plasma cells in primary immune thrombocytopenia
por: Yu, Tian-shu, et al.
Publicado: (2021)

Biological stratification of clinical disease courses in childhood immune thrombocytopenia
por: Schmidt, David E., et al.
Publicado: (2021)

Successful treatment of vaccine‐induced prothrombotic immune thrombocytopenia (VIPIT)
por: Thaler, Johannes, et al.
Publicado: (2021)

Combination of two complementary automated rapid assays for diagnosis of heparin‐induced thrombocytopenia (HIT)
por: Warkentin, Theodore E., et al.
Publicado: (2020)

Anti‐platelet antibodies in childhood immune thrombocytopenia: Prevalence and prognostic implications
por: Schmidt, David E., et al.
Publicado: (2020)

Combinations of rapid immunoassays for a speedy diagnosis of heparin‐induced thrombocytopenia
por: Rittener‐Ruff, Luana, et al.
Publicado: (2022)

Low-Dose Decitabine Inhibits Cytotoxic T Lymphocytes-Mediated Platelet Destruction via Modulating PD-1 Methylation in Immune Thrombocytopenia
por: Han, Panpan, et al.
Publicado: (2021)

Single platelet and megakaryocyte morpho-dynamics uncovered by multicolor reporter mouse strains in vitro and in vivo
por: Nicolai, Leo, et al.
Publicado: (2021)

Platelet dysfunction in platelet-type von Willebrand disease due to the constitutive triggering of the Lyn-PECAM1 inhibitory pathway
por: Bury, Loredana, et al.
Publicado: (2021)

Specific inhibition of the transporter MRP4/ABCC4 affects multiple signaling pathways and thrombus formation in human platelets
por: Wolf, Robert, et al.
Publicado: (2022)

Sorting nexin 24 is required for α-granule biogenesis and cargo delivery in megakaryocytes
por: Lacey, Joanne, et al.
Publicado: (2022)

The deglycosylated form of 1E12 inhibits platelet activation and prothrombotic effects induced by VITT antibodies
por: Vayne, Caroline, et al.
Publicado: (2022)

Iron- and erythropoietin-resistant anemia in a spontaneous breast cancer mouse model
por: Bregolat, Nuria Fabregas, et al.
Publicado: (2022)

Fc galactosylation of anti-platelet human IgG1 alloantibodies enhances complement activation on platelets
por: van Osch, Thijs L.J., et al.
Publicado: (2022)

Reduced platelet glycoprotein Ibα shedding accelerates thrombopoiesis and COX-1 recovery: implications for aspirin dosing regimen
por: Simeone, Paola, et al.
Publicado: (2022)

Immune-mediated thrombotic thrombocytopenic purpura plasma induces calcium- and IgG-dependent endothelial activation: correlations with disease severity
por: Tellier, Edwige, et al.
Publicado: (2022)

Measurement of procoagulant platelets provides mechanistic insight and diagnostic potential in heparin‐induced thrombocytopenia
por: Lee, Christine S. M., et al.
Publicado: (2022)

Temporal presentations of heparin‐induced thrombocytopenia following cardiac surgery: A single‐center, retrospective cohort study
por: Warkentin, Theodore E., et al.
Publicado: (2022)

A retrospective analysis of 122 immune thrombocytopenia patients treated with dapsone: Efficacy, safety and factors associated with treatment response
por: Colella, Marina P., et al.
Publicado: (2021)

The Copenhagen founder variant GP1BA c.58T>G is the most frequent cause of inherited thrombocytopenia in Denmark
por: Leinøe, Eva, et al.
Publicado: (2021)

Alice Silicon Strip Detector, test set up in laser box
por: xxx, x
Publicado: (2003)

COVID-19 vaccination in patients with immune thrombocytopenia
por: Visser, Chantal, et al.
Publicado: (2022)

Heparin Induced Thrombocytopenia in Patients with COVID-19
por: Warrior, Surbhi, et al.
Publicado: (2020)

Expanding the genetic spectrum of TUBB1-related thrombocytopenia
por: Palma-Barqueros, Verónica, et al.
Publicado: (2021)

Ribosome dysfunction underlies SLFN14-related thrombocytopenia
por: Ver Donck, Fabienne, et al.
Publicado: (2023)

Immune Thrombocytopenia Associated with COVID-19 - Case Series
por: Fatkhullin, Ramil, et al.
Publicado: (2020)

Does Thrombocytopenia Truly Correlate with COVID-19 Severity?
por: Hana, Caroline, et al.
Publicado: (2020)

Safety and efficacy of classical complement pathway inhibition with sutimlimab in chronic immune thrombocytopenia
por: Broome, Catherine M., et al.
Publicado: (2022)

Platelet variability index: a measure of platelet count fluctuations in patients with immune thrombocytopenia
por: Li, Na, et al.
Publicado: (2021)

Cost-effectiveness of eltrombopag vs intravenous immunoglobulin for the perioperative management of immune thrombocytopenia
por: Kaur, Manraj N., et al.
Publicado: (2022)

Indirubin modulates CD4(+) T‐cell homeostasis via PD1/PTEN/AKT signalling pathway in immune thrombocytopenia
por: Zhao, Yajing, et al.
Publicado: (2019)

IMMUNE THROMBOCYTOPENIA PURPURA FLARE POST SARS-COV-2 VACCINATION
por: Ali, Elrazi, et al.
Publicado: (2021)

Thrombocytopenia Associated with Increase in Disease Severity and Mortality in COVID-19 Patients
por: Banwait, Ranjit, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_eh789cndl2sku1tq2u2ts8t96c