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Disruption of polyhomeotic polymerization decreases nucleosome occupancy and alters genome accessibility

Chromatin attains its three-dimensional (3D) conformation by establishing contacts between different noncontiguous regions. Sterile Alpha Motif (SAM)–mediated polymerization of the polyhomeotic (PH) protein regulates subnuclear clustering of Polycomb Repressive Complex 1 (PRC1) and chromatin topolog...

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Detalles Bibliográficos
Autores principales:	Amin, Adfar, Kadam, Sangram, Mieczkowski, Jakub, Ahmed, Ikhlak, Bhat, Younus A, Shah, Fouziya, Tolstorukov, Michael Y, Kingston, Robert E, Padinhateeri, Ranjith, Wani, Ajazul H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Life Science Alliance LLC 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973501/ https://www.ncbi.nlm.nih.gov/pubmed/36849253 http://dx.doi.org/10.26508/lsa.202201768

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