Intrahost Monkeypox Virus Genome Variation in Patient with Early Infection, Finland, 2022

Monkeypox virus was imported into Finland during late May–early June 2022. Intrahost viral genome variation in a sample from 1 patient comprised a major variant with 3 lineage B.1.3–specific mutations and a minor variant with ancestral B.1 nucleotides. Results suggest either ongoing APOBEC3 enzyme–m...

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Detalles Bibliográficos
Autores principales: Vauhkonen, Hanna, Kallio-Kokko, Hannimari, Hiltunen-Back, Eija, Lönnqvist, Lasse, Leppäaho-Lakka, Jaana, Mannonen, Laura, Kant, Ravi, Sironen, Tarja, Kurkela, Satu, Lappalainen, Maija, Zorec, Tomaž Mark, Zakotnik, Samo, Vlaj, Doroteja, Korva, Miša, Avšič-Županc, Tatjana, Poljak, Mario, Smura, Teemu, Vapalahti, Olli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2023
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973688/
https://www.ncbi.nlm.nih.gov/pubmed/36703245
http://dx.doi.org/10.3201/eid2903.221388
Descripción
Sumario:Monkeypox virus was imported into Finland during late May–early June 2022. Intrahost viral genome variation in a sample from 1 patient comprised a major variant with 3 lineage B.1.3–specific mutations and a minor variant with ancestral B.1 nucleotides. Results suggest either ongoing APOBEC3 enzyme–mediated evolution or co-infection.

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