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Intrahost Monkeypox Virus Genome Variation in Patient with Early Infection, Finland, 2022

Monkeypox virus was imported into Finland during late May–early June 2022. Intrahost viral genome variation in a sample from 1 patient comprised a major variant with 3 lineage B.1.3–specific mutations and a minor variant with ancestral B.1 nucleotides. Results suggest either ongoing APOBEC3 enzyme–m...

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Autores principales: Vauhkonen, Hanna, Kallio-Kokko, Hannimari, Hiltunen-Back, Eija, Lönnqvist, Lasse, Leppäaho-Lakka, Jaana, Mannonen, Laura, Kant, Ravi, Sironen, Tarja, Kurkela, Satu, Lappalainen, Maija, Zorec, Tomaž Mark, Zakotnik, Samo, Vlaj, Doroteja, Korva, Miša, Avšič-Županc, Tatjana, Poljak, Mario, Smura, Teemu, Vapalahti, Olli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973688/
https://www.ncbi.nlm.nih.gov/pubmed/36703245
http://dx.doi.org/10.3201/eid2903.221388
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author Vauhkonen, Hanna
Kallio-Kokko, Hannimari
Hiltunen-Back, Eija
Lönnqvist, Lasse
Leppäaho-Lakka, Jaana
Mannonen, Laura
Kant, Ravi
Sironen, Tarja
Kurkela, Satu
Lappalainen, Maija
Zorec, Tomaž Mark
Zakotnik, Samo
Vlaj, Doroteja
Korva, Miša
Avšič-Županc, Tatjana
Poljak, Mario
Smura, Teemu
Vapalahti, Olli
author_facet Vauhkonen, Hanna
Kallio-Kokko, Hannimari
Hiltunen-Back, Eija
Lönnqvist, Lasse
Leppäaho-Lakka, Jaana
Mannonen, Laura
Kant, Ravi
Sironen, Tarja
Kurkela, Satu
Lappalainen, Maija
Zorec, Tomaž Mark
Zakotnik, Samo
Vlaj, Doroteja
Korva, Miša
Avšič-Županc, Tatjana
Poljak, Mario
Smura, Teemu
Vapalahti, Olli
author_sort Vauhkonen, Hanna
collection PubMed
description Monkeypox virus was imported into Finland during late May–early June 2022. Intrahost viral genome variation in a sample from 1 patient comprised a major variant with 3 lineage B.1.3–specific mutations and a minor variant with ancestral B.1 nucleotides. Results suggest either ongoing APOBEC3 enzyme–mediated evolution or co-infection.
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spelling pubmed-99736882023-03-01 Intrahost Monkeypox Virus Genome Variation in Patient with Early Infection, Finland, 2022 Vauhkonen, Hanna Kallio-Kokko, Hannimari Hiltunen-Back, Eija Lönnqvist, Lasse Leppäaho-Lakka, Jaana Mannonen, Laura Kant, Ravi Sironen, Tarja Kurkela, Satu Lappalainen, Maija Zorec, Tomaž Mark Zakotnik, Samo Vlaj, Doroteja Korva, Miša Avšič-Županc, Tatjana Poljak, Mario Smura, Teemu Vapalahti, Olli Emerg Infect Dis Research Letter Monkeypox virus was imported into Finland during late May–early June 2022. Intrahost viral genome variation in a sample from 1 patient comprised a major variant with 3 lineage B.1.3–specific mutations and a minor variant with ancestral B.1 nucleotides. Results suggest either ongoing APOBEC3 enzyme–mediated evolution or co-infection. Centers for Disease Control and Prevention 2023-03 /pmc/articles/PMC9973688/ /pubmed/36703245 http://dx.doi.org/10.3201/eid2903.221388 Text en https://creativecommons.org/licenses/by/4.0/Emerging Infectious Diseases is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Letter
Vauhkonen, Hanna
Kallio-Kokko, Hannimari
Hiltunen-Back, Eija
Lönnqvist, Lasse
Leppäaho-Lakka, Jaana
Mannonen, Laura
Kant, Ravi
Sironen, Tarja
Kurkela, Satu
Lappalainen, Maija
Zorec, Tomaž Mark
Zakotnik, Samo
Vlaj, Doroteja
Korva, Miša
Avšič-Županc, Tatjana
Poljak, Mario
Smura, Teemu
Vapalahti, Olli
Intrahost Monkeypox Virus Genome Variation in Patient with Early Infection, Finland, 2022
title Intrahost Monkeypox Virus Genome Variation in Patient with Early Infection, Finland, 2022
title_full Intrahost Monkeypox Virus Genome Variation in Patient with Early Infection, Finland, 2022
title_fullStr Intrahost Monkeypox Virus Genome Variation in Patient with Early Infection, Finland, 2022
title_full_unstemmed Intrahost Monkeypox Virus Genome Variation in Patient with Early Infection, Finland, 2022
title_short Intrahost Monkeypox Virus Genome Variation in Patient with Early Infection, Finland, 2022
title_sort intrahost monkeypox virus genome variation in patient with early infection, finland, 2022
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973688/
https://www.ncbi.nlm.nih.gov/pubmed/36703245
http://dx.doi.org/10.3201/eid2903.221388
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