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Possible Mpox Protection from Smallpox Vaccine–Generated Antibodies among Older Adults

Smallpox vaccination may confer cross-protection to mpox. We evaluated vaccinia virus antibodies in 162 persons ≥50 years of age in Spain; 68.5% had detectable antibodies. Highest coverage (78%) was among persons 71–80 years of age. Low antibody levels in 31.5% of this population indicates that addr...

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Autores principales: Sanz-Muñoz, Iván, Sánchez-dePrada, Laura, Sánchez-Martínez, Javier, Rojo-Rello, Silvia, Domínguez-Gil, Marta, Hernán-García, Cristina, Fernández-Espinilla, Virginia, de Lejarazu-Leonardo, Raúl Ortiz, Castrodeza-Sanz, Javier, Eiros, José María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973709/
https://www.ncbi.nlm.nih.gov/pubmed/36732061
http://dx.doi.org/10.3201/eid2903.221231
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author Sanz-Muñoz, Iván
Sánchez-dePrada, Laura
Sánchez-Martínez, Javier
Rojo-Rello, Silvia
Domínguez-Gil, Marta
Hernán-García, Cristina
Fernández-Espinilla, Virginia
de Lejarazu-Leonardo, Raúl Ortiz
Castrodeza-Sanz, Javier
Eiros, José María
author_facet Sanz-Muñoz, Iván
Sánchez-dePrada, Laura
Sánchez-Martínez, Javier
Rojo-Rello, Silvia
Domínguez-Gil, Marta
Hernán-García, Cristina
Fernández-Espinilla, Virginia
de Lejarazu-Leonardo, Raúl Ortiz
Castrodeza-Sanz, Javier
Eiros, José María
author_sort Sanz-Muñoz, Iván
collection PubMed
description Smallpox vaccination may confer cross-protection to mpox. We evaluated vaccinia virus antibodies in 162 persons ≥50 years of age in Spain; 68.5% had detectable antibodies. Highest coverage (78%) was among persons 71–80 years of age. Low antibody levels in 31.5% of this population indicates that addressing their vaccination should be a priority.
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spelling pubmed-99737092023-03-01 Possible Mpox Protection from Smallpox Vaccine–Generated Antibodies among Older Adults Sanz-Muñoz, Iván Sánchez-dePrada, Laura Sánchez-Martínez, Javier Rojo-Rello, Silvia Domínguez-Gil, Marta Hernán-García, Cristina Fernández-Espinilla, Virginia de Lejarazu-Leonardo, Raúl Ortiz Castrodeza-Sanz, Javier Eiros, José María Emerg Infect Dis Research Letter Smallpox vaccination may confer cross-protection to mpox. We evaluated vaccinia virus antibodies in 162 persons ≥50 years of age in Spain; 68.5% had detectable antibodies. Highest coverage (78%) was among persons 71–80 years of age. Low antibody levels in 31.5% of this population indicates that addressing their vaccination should be a priority. Centers for Disease Control and Prevention 2023-03 /pmc/articles/PMC9973709/ /pubmed/36732061 http://dx.doi.org/10.3201/eid2903.221231 Text en https://creativecommons.org/licenses/by/4.0/Emerging Infectious Diseases is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Letter
Sanz-Muñoz, Iván
Sánchez-dePrada, Laura
Sánchez-Martínez, Javier
Rojo-Rello, Silvia
Domínguez-Gil, Marta
Hernán-García, Cristina
Fernández-Espinilla, Virginia
de Lejarazu-Leonardo, Raúl Ortiz
Castrodeza-Sanz, Javier
Eiros, José María
Possible Mpox Protection from Smallpox Vaccine–Generated Antibodies among Older Adults
title Possible Mpox Protection from Smallpox Vaccine–Generated Antibodies among Older Adults
title_full Possible Mpox Protection from Smallpox Vaccine–Generated Antibodies among Older Adults
title_fullStr Possible Mpox Protection from Smallpox Vaccine–Generated Antibodies among Older Adults
title_full_unstemmed Possible Mpox Protection from Smallpox Vaccine–Generated Antibodies among Older Adults
title_short Possible Mpox Protection from Smallpox Vaccine–Generated Antibodies among Older Adults
title_sort possible mpox protection from smallpox vaccine–generated antibodies among older adults
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973709/
https://www.ncbi.nlm.nih.gov/pubmed/36732061
http://dx.doi.org/10.3201/eid2903.221231
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