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BosR and PlzA reciprocally regulate RpoS function to sustain Borrelia burgdorferi in ticks and mammals

The RNA polymerase alternative σ factor RpoS in Borrelia burgdorferi (Bb), the Lyme disease pathogen, is responsible for programmatic-positive and -negative gene regulation essential for the spirochete’s dual-host enzootic cycle. RpoS is expressed during tick-to-mammal transmission and throughout ma...

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Detalles Bibliográficos
Autores principales:	Grassmann, André A., Tokarz, Rafal, Golino, Caroline, McLain, Melissa A., Groshong, Ashley M., Radolf, Justin D., Caimano, Melissa J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974103/ https://www.ncbi.nlm.nih.gov/pubmed/36649080 http://dx.doi.org/10.1172/JCI166710

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