Solid lipid-based nanoparticulate system for sustained release and enhanced in-vitro cytotoxic effect of 5-fluorouracil on skin Melanoma and squamous cell carcinoma

The present study aimed to prepare solid lipid-based nanoparticles (SLNs) using Precirol(®) ATO 5 as solid lipid and Poloxamer 188 and Tween 80 as surfactant and co-surfactant respectively, and SLNs-derived gel for sustained delivery, enhanced in-vitro cytotoxicity, enhanced cellular uptake of 5-FU...

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Detalles Bibliográficos
Autores principales: Ali, Ahsan, Madni, Asadullah, Shah, Hassan, Jamshaid, Talha, Jan, Nasrullah, Khan, Safiullah, Khan, Muhammad Muzamil, Mahmood, Muhammad Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974133/
https://www.ncbi.nlm.nih.gov/pubmed/36854019
http://dx.doi.org/10.1371/journal.pone.0281004

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