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Effects of DNA Immunoadsorption Combined with Medication on Immune Function and Renal Function in Patients with Systemic Lupus Erythematosus

Objective. At present, glucocorticoids combined with cyclophosphamide are still used for the clinical treatment of systemic lupus erythematosus (SLE). However, long-term practice has shown that drug treatment currently has the phenomena of long treatment duration, uncontrollable conditions in a shor...

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Autores principales: Bai, Lijie, Sun, Mingxia, Wu, Guiying, Wang, Jing, Wang, Yong, Shi, Jun, Zhang, Liying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974245/
https://www.ncbi.nlm.nih.gov/pubmed/36864896
http://dx.doi.org/10.1155/2023/2843979
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author Bai, Lijie
Sun, Mingxia
Wu, Guiying
Wang, Jing
Wang, Yong
Shi, Jun
Zhang, Liying
author_facet Bai, Lijie
Sun, Mingxia
Wu, Guiying
Wang, Jing
Wang, Yong
Shi, Jun
Zhang, Liying
author_sort Bai, Lijie
collection PubMed
description Objective. At present, glucocorticoids combined with cyclophosphamide are still used for the clinical treatment of systemic lupus erythematosus (SLE). However, long-term practice has shown that drug treatment currently has the phenomena of long treatment duration, uncontrollable conditions in a short period of time, and unsatisfactory efficacy. DNA immunoadsorption therapy is a newly developed therapy. The combination of drugs and DNA immunoadsorption has been reported for the treatment of SLEN in clinics for a long time. In this study, we observed the effects of DNA immunoadsorption combined with drug therapy on immune function and renal function in patients with systemic lupus erythematosus (SLE). The results showed that the DNA immunosorbent assay combined with medication in the treatment of SLE could quickly and specifically remove pathogenic substances from patients, improve renal function, immune function, and complement levels in patients, and help to relieve disease activity.
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spelling pubmed-99742452023-03-01 Effects of DNA Immunoadsorption Combined with Medication on Immune Function and Renal Function in Patients with Systemic Lupus Erythematosus Bai, Lijie Sun, Mingxia Wu, Guiying Wang, Jing Wang, Yong Shi, Jun Zhang, Liying J Environ Public Health Research Article Objective. At present, glucocorticoids combined with cyclophosphamide are still used for the clinical treatment of systemic lupus erythematosus (SLE). However, long-term practice has shown that drug treatment currently has the phenomena of long treatment duration, uncontrollable conditions in a short period of time, and unsatisfactory efficacy. DNA immunoadsorption therapy is a newly developed therapy. The combination of drugs and DNA immunoadsorption has been reported for the treatment of SLEN in clinics for a long time. In this study, we observed the effects of DNA immunoadsorption combined with drug therapy on immune function and renal function in patients with systemic lupus erythematosus (SLE). The results showed that the DNA immunosorbent assay combined with medication in the treatment of SLE could quickly and specifically remove pathogenic substances from patients, improve renal function, immune function, and complement levels in patients, and help to relieve disease activity. Hindawi 2023-02-21 /pmc/articles/PMC9974245/ /pubmed/36864896 http://dx.doi.org/10.1155/2023/2843979 Text en Copyright © 2023 Lijie Bai et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Bai, Lijie
Sun, Mingxia
Wu, Guiying
Wang, Jing
Wang, Yong
Shi, Jun
Zhang, Liying
Effects of DNA Immunoadsorption Combined with Medication on Immune Function and Renal Function in Patients with Systemic Lupus Erythematosus
title Effects of DNA Immunoadsorption Combined with Medication on Immune Function and Renal Function in Patients with Systemic Lupus Erythematosus
title_full Effects of DNA Immunoadsorption Combined with Medication on Immune Function and Renal Function in Patients with Systemic Lupus Erythematosus
title_fullStr Effects of DNA Immunoadsorption Combined with Medication on Immune Function and Renal Function in Patients with Systemic Lupus Erythematosus
title_full_unstemmed Effects of DNA Immunoadsorption Combined with Medication on Immune Function and Renal Function in Patients with Systemic Lupus Erythematosus
title_short Effects of DNA Immunoadsorption Combined with Medication on Immune Function and Renal Function in Patients with Systemic Lupus Erythematosus
title_sort effects of dna immunoadsorption combined with medication on immune function and renal function in patients with systemic lupus erythematosus
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974245/
https://www.ncbi.nlm.nih.gov/pubmed/36864896
http://dx.doi.org/10.1155/2023/2843979
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