Cargando…

Mechanism of Xiezhuo Huayu Yiqi Tongluo Formula in the Treatment of Uric Acid Nephropathy Based on Network Pharmacology, Molecular Docking, and In Vivo Experiments

BACKGROUND: Xiezhuo Huayu Yiqi Tongluo Formula (XHYTF) consists of 14 Chinese herbal medicines. In this study, we investigated the potential mechanism of XHYTF in the treatment of uric acid nephropathy (UAN) through network pharmacology, molecular docking, and in vivo methods. METHODS: Using various...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fan, Lifei, Guo, Yuqin, Wu, Qingmei, Hu, Tingting, Chen, Xiaomei, Guo, Jing, Liu, Ying, Lu, Yuhui, Lin, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974263/ https://www.ncbi.nlm.nih.gov/pubmed/36865745 http://dx.doi.org/10.1155/2023/6931644

Ejemplares similares

Renoprotective Effect of Yiqi Yangyin Huayu Tongluo Formula against Diabetic Nephropathy in Diabetic Rats
por: Wang, Feng-li, et al.
Publicado: (2018)

Study on Intervention Mechanism of Yiqi Huayu Jiedu Decoction on ARDS Based on Network Pharmacology
por: Liang, Xu, et al.
Publicado: (2020)

Yiqi Jiedu Huayu Decoction Alleviates Renal Injury in Rats With Diabetic Nephropathy by Promoting Autophagy
por: Xuan, Chen, et al.
Publicado: (2021)

Network Pharmacology Study and Experimental Validation of Yiqi Huayu Decoction Inducing Ferroptosis in Gastric Cancer
por: Song, Siyuan, et al.
Publicado: (2022)

Huayu Tongluo Recipe Attenuates Renal Oxidative Stress and Inflammation through the Activation of AMPK/Nrf2 Signaling Pathway in Streptozotocin- (STZ-) Induced Diabetic Rats
por: Li, Yachun, et al.
Publicado: (2021)

Effect of Huayu Tongluo Herbs on Reduction of Proteinuria via Inhibition of Wnt/β-Catenin Signaling Pathway in Diabetic Rats
por: Bai, Lu, et al.
Publicado: (2017)

Yiqi Huayu decoction alleviates bleomycin-induced pulmonary fibrosis in rats by inhibiting senescence
por: Zuo, Biao, et al.
Publicado: (2022)

Effect of Yiqi Huayu Pinggan Zishen Formula Combined with Valsartan in the Treatment of Hypertension and Its Effect on MMP-9, Ang II, and MCP-1
por: Yan, Jing, et al.
Publicado: (2022)

Study on the mechanism of Shujin Tongluo granules in treating cervical spondylosis based on network pharmacology and molecular docking
por: Wang, Yixuan, et al.
Publicado: (2023)

Potential mechanism of Ziyin Tongluo Formula in the treatment of postmenopausal osteoporosis: based on network pharmacology and ovariectomized rat model
por: Chen, Rong-Bin, et al.
Publicado: (2021)

Retracted: Effect of Yiqi Huayu Pinggan Zishen Formula Combined with Valsartan in the Treatment of Hypertension and Its Effect on MMP-9, Ang II, and MCP-1
por: Methods in Medicine, Computational and Mathematical
Publicado: (2023)

Effects of Tiaopi Xiezhuo decoction on constipation and gut dysbiosis in patients with peritoneal dialysis
por: Peng, Yu, et al.
Publicado: (2023)

Effects and Action Mechanism of Huoxue Tongluo Formula on the Formation of Neutrophil Extracellular Traps
por: Zhou, Xiaoli, et al.
Publicado: (2022)

Deciphering the Pharmacological Mechanisms of the Huayu-Qiangshen-Tongbi Formula Through Integrating Network Pharmacology and In Vitro Pharmacological Investigation
por: Wang, Zihao, et al.
Publicado: (2019)

A network pharmacology approach to determine the underlying mechanisms of action of Yishen Tongluo formula for the treatment of oligoasthenozoospermia
por: Chen, Yangdi, et al.
Publicado: (2021)

Elucidation of the Mechanisms and Molecular Targets of Yiqi Shexue Formula for Treatment of Primary Immune Thrombocytopenia Based on Network Pharmacology
por: Jiang, Yunyao, et al.
Publicado: (2019)

Efficacy of Bushen Yiqi Huayu Decoction on Ovarian Reserve and Inflammatory Factors in Patients after Hysterectomy plus Salpingectomy
por: Zhang, Jinchun, et al.
Publicado: (2022)

Network pharmacology and molecular docking to explore the pharmacological mechanism of Yifei Tongluo granules in treating idiopathic pulmonary fibrosis: A review
por: Hou, Yuan, et al.
Publicado: (2023)

Pharmacological mechanisms of Fuzheng Huayu formula for Aristolochic acid I–induced kidney fibrosis through network pharmacology
por: Wang, Fan, et al.
Publicado: (2022)

Yishen Xiezhuo formula ameliorates the development of cisplatin-induced acute kidney injury by attenuating renal tubular epithelial cell senescence
por: Zhang, Qiaoying, et al.
Publicado: (2022)

Yiqi Huayu Jiedu Decoction Inhibits the Invasion and Metastasis of Gastric Cancer Cells through TGF-β/Smad Pathway
por: Wu, Ting-Ting, et al.
Publicado: (2017)

Effect of Yiqi Huayu Jiedu decoction on stages II and III gastric cancer: A multicenter, prospective, cohort study
por: Shu, Peng, et al.
Publicado: (2019)

The method of Yiqi Yangyin Tongluo can attenuate the pyroptosis of rheumatoid arthritis chondrocytes through the ASIC1a/NLRP3 signaling pathway
por: Zhao, Yeyu, et al.
Publicado: (2022)

Yiqi Huoxue Tongluo recipe regulates NR4A1 to improve renal mitochondrial function in unilateral ureteral obstruction (UUO) rats
por: He, Zhen, et al.
Publicado: (2022)

Corrigendum to “Yiqi Huayu Jiedu Decoction Inhibits the Invasion and Metastasis of Gastric Cancer Cells through TGF-β/Smad Pathway”
por: Wu, Ting-Ting, et al.
Publicado: (2021)

Antiliver Fibrosis Formula of Fuzheng Huayu Alleviates Inflammatory Response
por: Chang, Qing-Qi, et al.
Publicado: (2022)

Decoding the chemical composition and pharmacological mechanisms of Jiedu Tongluo Tiaogan Formula using high-performance liquid chromatography coupled with network pharmacology-based investigation
por: Zhang, Qi, et al.
Publicado: (2021)

The Influence of BuqiHuoxueTongluo Formula on Histopathology and Pulmonary Function Test in Bleomycin-Induced Idiopathic Pulmonary Fibrosis in Rats
por: Yu, Xiaolin, et al.
Publicado: (2018)

The Renal Protective Effect of Jiangya Tongluo Formula, through Regulation of Adrenomedullin and Angiotensin II, in Rats with Hypertensive Nephrosclerosis
por: Han, Lin, et al.
Publicado: (2015)

Qingfei Tongluo Formula Mitigates Mycoplasma pneumoniae Infection via the PERK Signaling Pathway
por: Liu, Xiuxiu, et al.
Publicado: (2022)

Effect of Fuzheng Huayu formula and its actions against liver fibrosis
por: Liu, Chenghai, et al.
Publicado: (2009)

The Mechanism Research of Qishen Yiqi Formula by Module-Network Analysis
por: Zheng, Shichao, et al.
Publicado: (2015)

Network Pharmacology Integrated Molecular Docking Revealed the Mechanism of Jianpi Yiqi Taohua Decoction Against Ulcerative Colitis
por: Jia, Lin, et al.
Publicado: (2022)

The Effect of Yiqi Huoxue Tongluo Decoction on Spinal Cord Microglia Activation and ASK1-MKK3-p38 Signal Pathway in Rats with Diabetic Neuropathic Pain
por: Wang, Fanjing, et al.
Publicado: (2022)

A Probe into the Intervention Mechanism of Yiqi Huayu Jiedu Decoction on TLR4/NLRP3 Signal Pathway in Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome (ARDS) Rats
por: Ma, Yuanhong, et al.
Publicado: (2022)

Repair mechanism of Yishen Tongluo formula on mouse sperm DNA fragmentation caused by polystyrene microplastics
por: Zhang, Chenming, et al.
Publicado: (2023)

Alleviation of Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome in Rats by Yiqi Huayu Jiedu Decoction: A Tandem Mass Tag-Based Proteomics Study
por: Luo, Chang-yong, et al.
Publicado: (2020)

Research on the Mechanism of Qushi Huayu Decoction in the Intervention of Nonalcoholic Fatty Liver Disease Based on Network Pharmacology and Molecular Docking Technology
por: Gao, Shan-shan, et al.
Publicado: (2020)

A clinical study of Yiqi Huayu Jiedu decoction reducing the risk of postoperative gastric cancer recurrence and metastasis: Study protocol for a randomized controlled trail
por: Hu, Yue, et al.
Publicado: (2020)

Clinical Efficacy Evaluation and Potential Mechanism of Zhishe Tongluo Capsule in the Treatment of Cerebral Infarction by Meta-Analysis Associated with Network Pharmacology
por: Geng, Zhi Xin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_bl3e8uk9jk4746nfkgdjbb66o0