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METTL3 Promotes Endothelium-Mesenchymal Transition of Pulmonary Artery Endothelial Cells by Regulating TRPC6/Calcineurin/NFAT Signaling Pathways

BACKGROUND: Endothelium-mesenchymal transition (EndMT) is a process of phenotypic and functional transition from activated endothelial cells to mesenchymal cells. Recently, EndMT has been proved to be one of the main pathological mechanisms of pulmonary artery hypertension (PAH). However, the molecu...

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Detalles Bibliográficos
Autores principales: Kong, Chunchu, Zhang, Fuxiu, Hu, Ruicheng, Wang, Lile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974285/
https://www.ncbi.nlm.nih.gov/pubmed/36865750
http://dx.doi.org/10.1155/2023/8269356