Enzyme-triggered deep tumor penetration of a dual-drug nanomedicine enables an enhanced cancer combination therapy

Cancer cells could be eradicated by promoting generation of excessive intracellular reactive oxygen species (ROS) via emerging nanomedicines. However, tumor heterogeneity and poor penetration of nanomedicines often lead to diverse levels of ROS production in the tumor site, and ROS at a low level pr...

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Detalles Bibliográficos
Autores principales: Gu, Lei, Duan, Zhenyu, Li, Xue, Li, Xin, Li, Yinggang, Li, Xiaoling, Xu, Gang, Gao, Peng, Zhang, Hu, Gu, Zhongwei, Chen, Jie, Gong, Qiyong, Luo, Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974368/
https://www.ncbi.nlm.nih.gov/pubmed/36875053
http://dx.doi.org/10.1016/j.bioactmat.2023.02.015

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