Cargando…

Microglia activation and neuronal alterations in retinas from COVID-19 patients: correlation with clinical parameters

BACKGROUND: Different ocular alterations have been described in patients with coronavirus disease 2019 (COVID-19). Our aim was to determine whether COVID-19 affected retinal cells and establish correlations with clinical parameters. METHODS: Retinal sections and flat-mount retinas from human donors...

Descripción completa

Detalles Bibliográficos
Autores principales:	Albertos-Arranz, Henar, Martínez-Gil, Natalia, Sánchez-Sáez, Xavier, Noailles, Agustina, Monferrer Adsuara, Clara, Remolí Sargues, Lidia, Pérez-Santonja, Juan J., Lax, Pedro, Calvo Andrés, Ramón, Cuenca, Nicolás
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974399/ https://www.ncbi.nlm.nih.gov/pubmed/36855168 http://dx.doi.org/10.1186/s40662-023-00329-2

Ejemplares similares

Ischemia-Reperfusion Increases TRPM7 Expression in Mouse Retinas
por: Martínez-Gil, Natalia, et al.
Publicado: (2023)

Incidental idiopathic intracranial hypertension
por: Sargues, Lidia Remolí, et al.
Publicado: (2021)

Microglia activation in a model of retinal degeneration and TUDCA neuroprotective effects
por: Noailles, Agustina, et al.
Publicado: (2014)

Neuroprotective Effects of Tauroursodeoxicholic Acid Involves Vascular and Glial Changes in Retinitis Pigmentosa Model
por: Fernández-Sánchez, Laura, et al.
Publicado: (2022)

Phenotypic Differences in a PRPH2 Mutation in Members of the Same Family Assessed with OCT and OCTA
por: Albertos-Arranz, Henar, et al.
Publicado: (2021)

The Absence of Toll-Like Receptor 4 Mildly Affects the Structure and Function in the Adult Mouse Retina
por: Noailles, Agustina, et al.
Publicado: (2019)

Systemic inflammation induced by lipopolysaccharide aggravates inherited retinal dystrophy
por: Noailles, Agustina, et al.
Publicado: (2018)

Prph2 knock-in mice recapitulate human central areolar choroidal dystrophy retinal degeneration and exhibit aberrant synaptic remodeling and microglial activation
por: Ruiz-Pastor, María José, et al.
Publicado: (2023)

Persistent inflammatory state after photoreceptor loss in an animal model of retinal degeneration
por: Noailles, Agustina, et al.
Publicado: (2016)

Natural Compounds from Saffron and Bear Bile Prevent Vision Loss and Retinal Degeneration
por: Fernández-Sánchez, Laura, et al.
Publicado: (2015)

Loss of Melanopsin-Expressing Ganglion Cell Subtypes and Dendritic Degeneration in the Aging Human Retina
por: Esquiva, Gema, et al.
Publicado: (2017)

Purinergic Receptors P2X7 and P2X4 as Markers of Disease Progression in the rd10 Mouse Model of Inherited Retinal Dystrophy
por: Martínez-Gil, Natalia, et al.
Publicado: (2022)

Microglia in the developing retina
por: Li, Fenge, et al.
Publicado: (2019)

Microglia in Cultured Porcine Retina: Qualitative Immunohistochemical Analyses of Reactive Microglia in the Outer Retina
por: Johansson, Kjell, et al.
Publicado: (2023)

Sodium Hyaluronate-Induced Ocular Hypertension in Rats Damages the Direction-Selective Circuit and Inner/Outer Retinal Plexiform Layers
por: Noailles, Agustina, et al.
Publicado: (2022)

Optical Coherence Tomography Angiography in Diabetic Patients: A Systematic Review
por: Boned-Murillo, Ana, et al.
Publicado: (2021)

Optical coherence tomography biomarkers in patients with macular edema secondary to retinal vein occlusion treated with dexamethasone implant
por: Castro-Navarro, Verónica, et al.
Publicado: (2022)

Intravitreal dexamethasone implant Ozurdex® in naïve and refractory patients with different subtypes of diabetic macular edema
por: Castro-Navarro, Verónica, et al.
Publicado: (2019)

Culture and Characterization of Microglia from the Adult Murine Retina
por: Devarajan, Gayathri, et al.
Publicado: (2014)

ADPβS evokes microglia activation in the rabbit retina in vivo
por: Uckermann, Ortrud, et al.
Publicado: (2005)

Isolation of microglia from retinas of chronic ocular hypertensive rats
por: Zhong, Huimin, et al.
Publicado: (2021)

Gradual Increase in Environmental Light Intensity Induces Oxidative Stress and Inflammation and Accelerates Retinal Neurodegeneration
por: Kutsyr, Oksana, et al.
Publicado: (2020)

Synthesis and Propagation of Complement C3 by Microglia/Monocytes in the Aging Retina
por: Rutar, Matt, et al.
Publicado: (2014)

Occurrence of Transmembrane Protein 119 in the Retina is Not Restricted to the Microglia: An Immunohistochemical Study
por: Su, Nan, et al.
Publicado: (2019)

More than meets the eye: The role of microglia in healthy and diseased retina
por: Murenu, Elisa, et al.
Publicado: (2022)

Editorial: Exploiting new methods to study microglia in healthy and diseased retina
por: Lennikov, Anton, et al.
Publicado: (2023)

Formation of Müller glia-derived progenitor cells in retinas depleted of microglia
por: El-Hodiri, Heithem M., et al.
Publicado: (2023)

Starburst amacrine cells, involved in visual motion perception, lose their synaptic input from dopaminergic amacrine cells and degenerate in Parkinson’s disease patients
por: Sánchez-Sáez, Xavier, et al.
Publicado: (2023)

Correction: Starburst amacrine cells, involved in visual motion perception, lose their synaptic input from dopaminergic amacrine cells and degenerate in Parkinson’s disease patients
por: Sánchez‑Sáez, Xavier, et al.
Publicado: (2023)

Indole-3-carbinol regulates microglia homeostasis and protects the retina from degeneration
por: Khan, Amir Saeed, et al.
Publicado: (2020)

MICROGLIA MAY INSTRUCT SYNAPTIC FATE VIA SIRPα IN MOUSE RETINA
por: Jiang, Danye, et al.
Publicado: (2019)

Trogocytosis of neurons and glial cells by microglia in a healthy adult macaque retina
por: Goyal, Megan, et al.
Publicado: (2023)

UVA induces retinal photoreceptor cell death via receptor interacting protein 3 kinase mediated necroptosis
por: Yu, Zhen, et al.
Publicado: (2022)

Expression of Inducible Nitric Oxide Synthase (iNOS) in Microglia of the Developing Quail Retina
por: Sierra, Ana, et al.
Publicado: (2014)

Minocycline counter-regulates pro-inflammatory microglia responses in the retina and protects from degeneration
por: Scholz, Rebecca, et al.
Publicado: (2015)

Microglia preserve visual function in the aging retina by supporting retinal pigment epithelial health
por: Karg, Margarete M., et al.
Publicado: (2023)

Fate mapping reveals that microglia and recruited monocyte-derived macrophages are definitively distinguishable by phenotype in the retina
por: O’Koren, E. G., et al.
Publicado: (2016)

Nanoparticle-based targeting of microglia improves the neural regeneration enhancing effects of immunosuppression in the zebrafish retina
por: Emmerich, Kevin, et al.
Publicado: (2023)

Correction: Microglia preserve visual function in the aging retina by supporting retinal pigment epithelial health
por: Karg, Margarete M., et al.
Publicado: (2023)

Inherited Retinal Dystrophies: Role of Oxidative Stress and Inflammation in Their Physiopathology and Therapeutic Implications
por: Pinilla, Isabel, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_8gsnroviuo1v36joljifq6ohtd