Cargando…

Mitochondrial control of microglial phagocytosis by the translocator protein and hexokinase 2 in Alzheimer’s disease

Microglial phagocytosis is an energetically demanding process that plays a critical role in the removal of toxic protein aggregates in Alzheimer’s disease (AD). Recent evidence indicates that a switch in energy production from mitochondrial respiration to glycolysis disrupts this important protectiv...

Descripción completa

Detalles Bibliográficos
Autores principales: Fairley, Lauren H., Lai, Kei Onn, Wong, Jia Hui, Chong, Wei Jing, Vincent, Anselm Salvatore, D’Agostino, Giuseppe, Wu, Xiaoting, Naik, Roshan R., Jayaraman, Anusha, Langley, Sarah R., Ruedl, Christiane, Barron, Anna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974442/
https://www.ncbi.nlm.nih.gov/pubmed/36787364
http://dx.doi.org/10.1073/pnas.2209177120