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Mitochondrial control of microglial phagocytosis by the translocator protein and hexokinase 2 in Alzheimer’s disease
Microglial phagocytosis is an energetically demanding process that plays a critical role in the removal of toxic protein aggregates in Alzheimer’s disease (AD). Recent evidence indicates that a switch in energy production from mitochondrial respiration to glycolysis disrupts this important protectiv...
Autores principales: | Fairley, Lauren H., Lai, Kei Onn, Wong, Jia Hui, Chong, Wei Jing, Vincent, Anselm Salvatore, D’Agostino, Giuseppe, Wu, Xiaoting, Naik, Roshan R., Jayaraman, Anusha, Langley, Sarah R., Ruedl, Christiane, Barron, Anna M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974442/ https://www.ncbi.nlm.nih.gov/pubmed/36787364 http://dx.doi.org/10.1073/pnas.2209177120 |
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