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Cytoskeletal association of ATP citrate lyase controls the mechanodynamics of macropinocytosis

Macropinocytosis is an actin-dependent mode of nonselective endocytosis that mediates the uptake of extracellular fluid-phase cargoes. It is now well recognized that tumor cells exploit macropinocytosis to internalize macromolecules that can be catabolized and used to support cell growth and prolife...

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Detalles Bibliográficos
Autores principales: Puccini, Joseph, Wei, Jia, Tong, Liang, Bar-Sagi, Dafna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974455/
https://www.ncbi.nlm.nih.gov/pubmed/36787367
http://dx.doi.org/10.1073/pnas.2213272120