Cargando…
The energetics of rapid cellular mechanotransduction
Cells throughout the human body detect mechanical forces. While it is known that the rapid (millisecond) detection of mechanical forces is mediated by force-gated ion channels, a detailed quantitative understanding of cells as sensors of mechanical energy is still lacking. Here, we combine atomic fo...
Autores principales: | Young, Michael N., Sindoni, Michael J., Lewis, Amanda H., Zauscher, Stefan, Grandl, Jörg |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974467/ https://www.ncbi.nlm.nih.gov/pubmed/36795747 http://dx.doi.org/10.1073/pnas.2215747120 |
Ejemplares similares
-
Physics of mechanotransduction by Piezo ion channels
por: Young, Michael, et al.
Publicado: (2022) -
Mechanical sensitivity of Piezo1 ion channels can be tuned by cellular membrane tension
por: Lewis, Amanda H, et al.
Publicado: (2015) -
Dystrophin missense mutations alter focal adhesion tension and mechanotransduction
por: Ramirez, Maria Paz, et al.
Publicado: (2022) -
Mitochondria-localized AMPK responds to local energetics and contributes to exercise and energetic stress-induced mitophagy
por: Drake, Joshua C., et al.
Publicado: (2021) -
An ensemble of flexible conformations underlies mechanotransduction by the cadherin–catenin adhesion complex
por: Bush, Martin, et al.
Publicado: (2019)