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The circadian demethylation of a unique intronic deoxymethylCpG-rich island boosts the transcription of its cognate circadian clock output gene

We demonstrate that there is a tight functional relationship between two highly evolutionary conserved cell processes, i.e., the circadian clock (CC) and the circadian DNA demethylation–methylation of cognate deoxyCpG-rich islands. We have discovered that every circadian clock-controlled output gene...

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Detalles Bibliográficos
Autores principales: Misra, Nisha, Damara, Manohar, Ye, Tao, Chambon, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974474/
https://www.ncbi.nlm.nih.gov/pubmed/36791105
http://dx.doi.org/10.1073/pnas.2214062120

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