The SET oncoprotein promotes estrogen-induced transcription by facilitating establishment of active chromatin

SET is a multifunctional histone-binding oncoprotein that regulates transcription by an unclear mechanism. Here we show that SET enhances estrogen-dependent transcription. SET knockdown abrogates transcription of estrogen-responsive genes and their enhancer RNAs. In response to 17β-estradiol (E2), S...

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Detalles Bibliográficos
Autores principales: Guo, Changying, Meza-Sosa, Karla F., Valle-Garcia, David, Zhao, Guomeng, Gao, Kun, Yu, Liting, Zhang, Hongying, Chen, Yeqing, Sun, Liang, Rockowitz, Shira, Wang, Shouyu, Jiang, Sheng, Lieberman, Judy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974495/
https://www.ncbi.nlm.nih.gov/pubmed/36791099
http://dx.doi.org/10.1073/pnas.2206878120

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