A review on the role of long non-coding RNA prostate androgen-regulated transcript 1 (PART1) in the etiology of different disorders

LncRNA prostate androgen-regulated transcript 1 (PART1) is an important lncRNA in the carcinogenesis whose role has been firstly unraveled in prostate cancer. Expression of this lncRNA is activated by androgen in prostate cancer cells. In addition, this lncRNA has a role in the pathogenesis interver...

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Autores principales: Ghafouri-Fard, Soudeh, Harsij, Atefeh, Hussen, Bashdar Mahmud, Abdullah, Snur Rasool, Baniahmad, Aria, Taheri, Mohammad, Sharifi, Guive
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974648/
https://www.ncbi.nlm.nih.gov/pubmed/36875771
http://dx.doi.org/10.3389/fcell.2023.1124615
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author Ghafouri-Fard, Soudeh
Harsij, Atefeh
Hussen, Bashdar Mahmud
Abdullah, Snur Rasool
Baniahmad, Aria
Taheri, Mohammad
Sharifi, Guive
author_facet Ghafouri-Fard, Soudeh
Harsij, Atefeh
Hussen, Bashdar Mahmud
Abdullah, Snur Rasool
Baniahmad, Aria
Taheri, Mohammad
Sharifi, Guive
author_sort Ghafouri-Fard, Soudeh
collection PubMed
description LncRNA prostate androgen-regulated transcript 1 (PART1) is an important lncRNA in the carcinogenesis whose role has been firstly unraveled in prostate cancer. Expression of this lncRNA is activated by androgen in prostate cancer cells. In addition, this lncRNA has a role in the pathogenesis intervertebral disc degeneration, myocardial ischemia-reperfusion injury, osteoarthritis, osteoporosis and Parkinson’s disease. Diagnostic role of PART1 has been assessed in some types of cancers. Moreover, dysregulation of PART1 expression is regarded as a prognostic factor in a variety of cancers. The current review provides a concise but comprehensive summary of the role of PART1 in different cancers and non-malignant disorders.
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spelling pubmed-99746482023-03-02 A review on the role of long non-coding RNA prostate androgen-regulated transcript 1 (PART1) in the etiology of different disorders Ghafouri-Fard, Soudeh Harsij, Atefeh Hussen, Bashdar Mahmud Abdullah, Snur Rasool Baniahmad, Aria Taheri, Mohammad Sharifi, Guive Front Cell Dev Biol Cell and Developmental Biology LncRNA prostate androgen-regulated transcript 1 (PART1) is an important lncRNA in the carcinogenesis whose role has been firstly unraveled in prostate cancer. Expression of this lncRNA is activated by androgen in prostate cancer cells. In addition, this lncRNA has a role in the pathogenesis intervertebral disc degeneration, myocardial ischemia-reperfusion injury, osteoarthritis, osteoporosis and Parkinson’s disease. Diagnostic role of PART1 has been assessed in some types of cancers. Moreover, dysregulation of PART1 expression is regarded as a prognostic factor in a variety of cancers. The current review provides a concise but comprehensive summary of the role of PART1 in different cancers and non-malignant disorders. Frontiers Media S.A. 2023-02-15 /pmc/articles/PMC9974648/ /pubmed/36875771 http://dx.doi.org/10.3389/fcell.2023.1124615 Text en Copyright © 2023 Ghafouri-Fard, Harsij, Hussen, Abdullah, Baniahmad, Taheri and Sharifi. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cell and Developmental Biology
Ghafouri-Fard, Soudeh
Harsij, Atefeh
Hussen, Bashdar Mahmud
Abdullah, Snur Rasool
Baniahmad, Aria
Taheri, Mohammad
Sharifi, Guive
A review on the role of long non-coding RNA prostate androgen-regulated transcript 1 (PART1) in the etiology of different disorders
title A review on the role of long non-coding RNA prostate androgen-regulated transcript 1 (PART1) in the etiology of different disorders
title_full A review on the role of long non-coding RNA prostate androgen-regulated transcript 1 (PART1) in the etiology of different disorders
title_fullStr A review on the role of long non-coding RNA prostate androgen-regulated transcript 1 (PART1) in the etiology of different disorders
title_full_unstemmed A review on the role of long non-coding RNA prostate androgen-regulated transcript 1 (PART1) in the etiology of different disorders
title_short A review on the role of long non-coding RNA prostate androgen-regulated transcript 1 (PART1) in the etiology of different disorders
title_sort review on the role of long non-coding rna prostate androgen-regulated transcript 1 (part1) in the etiology of different disorders
topic Cell and Developmental Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974648/
https://www.ncbi.nlm.nih.gov/pubmed/36875771
http://dx.doi.org/10.3389/fcell.2023.1124615
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