In silico prediction and in vivo testing of promoters targeting GABAergic inhibitory neurons

Impairment of GABAergic inhibitory neuronal function is linked to epilepsy and other neurological and psychiatric disorders. Recombinant adeno-associated virus (rAAV)-based gene therapy targeting GABAergic neurons is a promising treatment for GABA-associated disorders. However, there is a need to de...

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Detalles Bibliográficos
Autores principales: Niibori, Yosuke, Duba-Kiss, Robert, Bruder, Joseph T., Smith, Jared B., Hampson, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974971/
https://www.ncbi.nlm.nih.gov/pubmed/36874244
http://dx.doi.org/10.1016/j.omtm.2023.01.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974971/
https://www.ncbi.nlm.nih.gov/pubmed/36874244
http://dx.doi.org/10.1016/j.omtm.2023.01.007

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