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In silico prediction and in vivo testing of promoters targeting GABAergic inhibitory neurons
Impairment of GABAergic inhibitory neuronal function is linked to epilepsy and other neurological and psychiatric disorders. Recombinant adeno-associated virus (rAAV)-based gene therapy targeting GABAergic neurons is a promising treatment for GABA-associated disorders. However, there is a need to de...
Autores principales: | Niibori, Yosuke, Duba-Kiss, Robert, Bruder, Joseph T., Smith, Jared B., Hampson, David R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974971/ https://www.ncbi.nlm.nih.gov/pubmed/36874244 http://dx.doi.org/10.1016/j.omtm.2023.01.007 |
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