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Efficacy of oligodendrocyte precursor cells as delivery vehicles for single-chain variable fragment to misfolded SOD1 in ALS rat model

Superoxide dismutase1 (SOD 1) mutation is a leading cause of familial amyotrophic lateral sclerosis (ALS). Growing evidence suggests that antibody therapy against misfolded SOD1 protein can be therapeutic. However, the therapeutic effects are limited, partly because of the delivery system. Therefore...

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Detalles Bibliográficos
Autores principales:	Minamiyama, Sumio, Sakai, Madoka, Yamaguchi, Yuko, Kusui, Makiko, Wada, Hideki, Hikiami, Ryota, Tamaki, Yoshitaka, Asada-Utsugi, Megumi, Shodai, Akemi, Makino, Akiko, Fujiwara, Noriko, Ayaki, Takashi, Maki, Takakuni, Warita, Hitoshi, Aoki, Masashi, Tomonaga, Keizo, Takahashi, Ryosuke, Urushitani, Makoto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974989/ https://www.ncbi.nlm.nih.gov/pubmed/36874245 http://dx.doi.org/10.1016/j.omtm.2023.01.008

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