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Cell surface protein aggregation triggers endocytosis to maintain plasma membrane proteostasis

The ability of cells to manage consequences of exogenous proteotoxicity is key to cellular homeostasis. While a plethora of well-characterised machinery aids intracellular proteostasis, mechanisms involved in the response to denaturation of extracellular proteins remain elusive. Here we show that ag...

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Detalles Bibliográficos
Autores principales: Paul, David, Stern, Omer, Vallis, Yvonne, Dhillon, Jatinder, Buchanan, Andrew, McMahon, Harvey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9974993/
https://www.ncbi.nlm.nih.gov/pubmed/36854675
http://dx.doi.org/10.1038/s41467-023-36496-y

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