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MESP2 binds competitively to TCF4 to suppress gastric cancer progression by regulating the SKP2/p27 axis

Gastric cancer (GC) is a major cause of human deaths worldwide, and is notorious for its high incidence and mortality rates. Mesoderm Posterior Basic Helix-loop-helix (bHLH) transcription factor 2 (MESP2) acts as a transcription factor with a conserved bHLH domain. However, whether MESP2 contributes...

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Detalles Bibliográficos
Autores principales: Ge, Lingjun, Zhao, Gaichao, Lan, Chao, Song, Houji, Qi, Dan, Huang, Pan, Ke, Xiaoxue, Cui, Hongjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975210/
https://www.ncbi.nlm.nih.gov/pubmed/36854722
http://dx.doi.org/10.1038/s41420-023-01367-4