Comprehensive profiling of EGFR mutation subtypes reveals genomic-clinical associations in non-small-cell lung cancer patients on first-generation EGFR inhibitors

Common sensitizing mutations in epidermal growth factor receptor (cEGFR), including exon 19 deletions (19-Del) and exon 21 L858R substitution, are associated with high sensitivity to EGFR-TKIs in NSCLC patients. The treatment for NSCLC patients with uncommon EGFR (uEGFR) mutations remains a subject...

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Detalles Bibliográficos
Autores principales: Bai, Yongkang, Liu, Xiang, Zheng, Limin, Wang, Song, Zhang, Junli, Xiong, Shi, Zhang, Pengfei, Jiao, Zichen, Zhao, Gefei, Zhou, Chu, Pang, Jiaohui, Xu, Yang, Ou, Qiuxiang, Mao, Yuan, Zhang, Louqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975296/
https://www.ncbi.nlm.nih.gov/pubmed/36804751
http://dx.doi.org/10.1016/j.neo.2023.100888

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