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A tour de force provides novel insights into CD19-CAR T cell resistance mechanisms

Sworder et al.(1) developed an integrated simultaneous tumor and effector profiling (STEP) approach to study resistance mechanisms to CD19-CAR T cell therapy in large B-cell lymphomas. Their study provides novel biological insights and paves the way for future interventions.

Detalles Bibliográficos
Autores principales: Talleur, Aimee C., Gottschalk, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975327/
https://www.ncbi.nlm.nih.gov/pubmed/36812888
http://dx.doi.org/10.1016/j.xcrm.2023.100949
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author Talleur, Aimee C.
Gottschalk, Stephen
author_facet Talleur, Aimee C.
Gottschalk, Stephen
author_sort Talleur, Aimee C.
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description Sworder et al.(1) developed an integrated simultaneous tumor and effector profiling (STEP) approach to study resistance mechanisms to CD19-CAR T cell therapy in large B-cell lymphomas. Their study provides novel biological insights and paves the way for future interventions.
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spelling pubmed-99753272023-03-02 A tour de force provides novel insights into CD19-CAR T cell resistance mechanisms Talleur, Aimee C. Gottschalk, Stephen Cell Rep Med Spotlight Sworder et al.(1) developed an integrated simultaneous tumor and effector profiling (STEP) approach to study resistance mechanisms to CD19-CAR T cell therapy in large B-cell lymphomas. Their study provides novel biological insights and paves the way for future interventions. Elsevier 2023-02-21 /pmc/articles/PMC9975327/ /pubmed/36812888 http://dx.doi.org/10.1016/j.xcrm.2023.100949 Text en © 2023 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Spotlight
Talleur, Aimee C.
Gottschalk, Stephen
A tour de force provides novel insights into CD19-CAR T cell resistance mechanisms
title A tour de force provides novel insights into CD19-CAR T cell resistance mechanisms
title_full A tour de force provides novel insights into CD19-CAR T cell resistance mechanisms
title_fullStr A tour de force provides novel insights into CD19-CAR T cell resistance mechanisms
title_full_unstemmed A tour de force provides novel insights into CD19-CAR T cell resistance mechanisms
title_short A tour de force provides novel insights into CD19-CAR T cell resistance mechanisms
title_sort tour de force provides novel insights into cd19-car t cell resistance mechanisms
topic Spotlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975327/
https://www.ncbi.nlm.nih.gov/pubmed/36812888
http://dx.doi.org/10.1016/j.xcrm.2023.100949
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