Disease-associated oligodendrocyte signatures are spatiotemporally dysregulated in spinocerebellar ataxia type 3

Spinocerebellar ataxia type 3 (SCA3) is a neurodegenerative disease caused by a CAG repeat expansion in the ATXN3 gene. Though the ATXN3 protein is expressed ubiquitously throughout the CNS, regional pathology in SCA3 patients is observed within select neuronal populations and more recently within o...

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Detalles Bibliográficos
Autores principales: Schuster, Kristen H., DiFranco, Danielle M., Putka, Alexandra F., Mato, Juan P., Jarrah, Sabrina I., Stec, Nicholas R., Sundararajan, Vikram O., McLoughlin, Hayley S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975394/
https://www.ncbi.nlm.nih.gov/pubmed/36875652
http://dx.doi.org/10.3389/fnins.2023.1118429

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