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Metastatic Colorectal Cancer Treatment Response Evaluation by Ultra-Deep Sequencing of Cell-Free DNA and Matched White Blood Cells

PURPOSE: Circulating tumor DNA (ctDNA) has the potential to guide therapy selection and monitor treatment response in patients with metastatic cancer. However, germline and clonal hematopoiesis–associated alterations can confound identification of tumor-specific mutations in cell-free DNA (cfDNA), o...

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Detalles Bibliográficos
Autores principales: van 't Erve, Iris, Medina, Jamie E., Leal, Alessandro, Papp, Eniko, Phallen, Jillian, Adleff, Vilmos, Chiao, Elaine Jiayuee, Arun, Adith S., Bolhuis, Karen, Simmons, John K., Karandikar, Aanavi, Valkenburg, Kenneth C., Sausen, Mark, Angiuoli, Samuel V., Scharpf, Robert B., Punt, Cornelis J.A., Meijer, Gerrit A., Velculescu, Victor E., Fijneman, Remond J.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975664/
https://www.ncbi.nlm.nih.gov/pubmed/36534496
http://dx.doi.org/10.1158/1078-0432.CCR-22-2538