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Metastatic Colorectal Cancer Treatment Response Evaluation by Ultra-Deep Sequencing of Cell-Free DNA and Matched White Blood Cells
PURPOSE: Circulating tumor DNA (ctDNA) has the potential to guide therapy selection and monitor treatment response in patients with metastatic cancer. However, germline and clonal hematopoiesis–associated alterations can confound identification of tumor-specific mutations in cell-free DNA (cfDNA), o...
Autores principales: | van 't Erve, Iris, Medina, Jamie E., Leal, Alessandro, Papp, Eniko, Phallen, Jillian, Adleff, Vilmos, Chiao, Elaine Jiayuee, Arun, Adith S., Bolhuis, Karen, Simmons, John K., Karandikar, Aanavi, Valkenburg, Kenneth C., Sausen, Mark, Angiuoli, Samuel V., Scharpf, Robert B., Punt, Cornelis J.A., Meijer, Gerrit A., Velculescu, Victor E., Fijneman, Remond J.A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975664/ https://www.ncbi.nlm.nih.gov/pubmed/36534496 http://dx.doi.org/10.1158/1078-0432.CCR-22-2538 |
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