A Ubiquitination Cascade Regulating the Integrated Stress Response and Survival in Carcinomas

Systematic identification of signaling pathways required for the fitness of cancer cells will facilitate the development of new cancer therapies. We used gene essentiality measurements in 1,086 cancer cell lines to identify selective coessentiality modules and found that a ubiquitin ligase complex c...

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Detalles Bibliográficos
Autores principales: Cervia, Lisa D., Shibue, Tsukasa, Borah, Ashir A., Gaeta, Benjamin, He, Linh, Leung, Lisa, Li, Naomi, Moyer, Sydney M., Shim, Brian H., Dumont, Nancy, Gonzalez, Alfredo, Bick, Nolan R., Kazachkova, Mariya, Dempster, Joshua M., Krill-Burger, John Michael, Piccioni, Federica, Udeshi, Namrata D., Olive, Meagan E., Carr, Steven A., Root, David E., McFarland, James M., Vazquez, Francisca, Hahn, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975667/
https://www.ncbi.nlm.nih.gov/pubmed/36576405
http://dx.doi.org/10.1158/2159-8290.CD-22-1230

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