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Occlusion preconditioned mice are resilient to hypobaric hypoxia-induced myocarditis and arrhythmias due to enhanced immunomodulation, metabolic homeostasis, and antioxidants defense

BACKGROUND: Sea-level residents experience altitude sickness when they hike or visit altitudes above ~2,500 m due to the hypobaric hypoxia (HH) conditions at such places. HH has been shown to drive cardiac inflammation in both ventricles by inducing maladaptive metabolic reprogramming of macrophages...

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Detalles Bibliográficos
Autores principales: Adzika, Gabriel Komla, Mprah, Richard, Rizvi, Ruqayya, Adekunle, Adebayo Oluwafemi, Ndzie Noah, Marie Louise, Wowui, Prosperl Ivette, Adzraku, Seyram Yao, Adu-Amankwaah, Joseph, Wang, Fengli, Lin, Yuwen, Fu, Lu, Liu, Xiaomei, Xiang, Jie, Sun, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975755/
https://www.ncbi.nlm.nih.gov/pubmed/36875113
http://dx.doi.org/10.3389/fimmu.2023.1124649