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Occlusion preconditioned mice are resilient to hypobaric hypoxia-induced myocarditis and arrhythmias due to enhanced immunomodulation, metabolic homeostasis, and antioxidants defense
BACKGROUND: Sea-level residents experience altitude sickness when they hike or visit altitudes above ~2,500 m due to the hypobaric hypoxia (HH) conditions at such places. HH has been shown to drive cardiac inflammation in both ventricles by inducing maladaptive metabolic reprogramming of macrophages...
Autores principales: | Adzika, Gabriel Komla, Mprah, Richard, Rizvi, Ruqayya, Adekunle, Adebayo Oluwafemi, Ndzie Noah, Marie Louise, Wowui, Prosperl Ivette, Adzraku, Seyram Yao, Adu-Amankwaah, Joseph, Wang, Fengli, Lin, Yuwen, Fu, Lu, Liu, Xiaomei, Xiang, Jie, Sun, Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975755/ https://www.ncbi.nlm.nih.gov/pubmed/36875113 http://dx.doi.org/10.3389/fimmu.2023.1124649 |
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