Strategies for Conditional Regulation of Proteins

[Image: see text] Design of the next-generation of therapeutics, biosensors, and molecular tools for basic research requires that we bring protein activity under control. Each protein has unique properties, and therefore, it is critical to tailor the current techniques to develop new regulatory meth...

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Autores principales: Nadendla, Karthik, Simpson, Grant G., Becher, Julie, Journeaux, Toby, Cabeza-Cabrerizo, Mar, Bernardes, Gonçalo J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975842/
https://www.ncbi.nlm.nih.gov/pubmed/36873677
http://dx.doi.org/10.1021/jacsau.2c00654
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author Nadendla, Karthik
Simpson, Grant G.
Becher, Julie
Journeaux, Toby
Cabeza-Cabrerizo, Mar
Bernardes, Gonçalo J. L.
author_facet Nadendla, Karthik
Simpson, Grant G.
Becher, Julie
Journeaux, Toby
Cabeza-Cabrerizo, Mar
Bernardes, Gonçalo J. L.
author_sort Nadendla, Karthik
collection PubMed
description [Image: see text] Design of the next-generation of therapeutics, biosensors, and molecular tools for basic research requires that we bring protein activity under control. Each protein has unique properties, and therefore, it is critical to tailor the current techniques to develop new regulatory methods and regulate new proteins of interest (POIs). This perspective gives an overview of the widely used stimuli and synthetic and natural methods for conditional regulation of proteins.
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spelling pubmed-99758422023-03-02 Strategies for Conditional Regulation of Proteins Nadendla, Karthik Simpson, Grant G. Becher, Julie Journeaux, Toby Cabeza-Cabrerizo, Mar Bernardes, Gonçalo J. L. JACS Au [Image: see text] Design of the next-generation of therapeutics, biosensors, and molecular tools for basic research requires that we bring protein activity under control. Each protein has unique properties, and therefore, it is critical to tailor the current techniques to develop new regulatory methods and regulate new proteins of interest (POIs). This perspective gives an overview of the widely used stimuli and synthetic and natural methods for conditional regulation of proteins. American Chemical Society 2023-01-26 /pmc/articles/PMC9975842/ /pubmed/36873677 http://dx.doi.org/10.1021/jacsau.2c00654 Text en © 2023 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by/4.0/Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Nadendla, Karthik
Simpson, Grant G.
Becher, Julie
Journeaux, Toby
Cabeza-Cabrerizo, Mar
Bernardes, Gonçalo J. L.
Strategies for Conditional Regulation of Proteins
title Strategies for Conditional Regulation of Proteins
title_full Strategies for Conditional Regulation of Proteins
title_fullStr Strategies for Conditional Regulation of Proteins
title_full_unstemmed Strategies for Conditional Regulation of Proteins
title_short Strategies for Conditional Regulation of Proteins
title_sort strategies for conditional regulation of proteins
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975842/
https://www.ncbi.nlm.nih.gov/pubmed/36873677
http://dx.doi.org/10.1021/jacsau.2c00654
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