Structural mechanism of CRL4‐instructed STAT2 degradation via a novel cytomegaloviral DCAF receptor

Human cytomegalovirus (CMV) is a ubiquitously distributed pathogen whose rodent counterparts such as mouse and rat CMV serve as common infection models. Here, we conducted global proteome profiling of rat CMV‐infected cells and uncovered a pronounced loss of the transcription factor STAT2, which is...

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Detalles Bibliográficos
Autores principales: Le‐Trilling, Vu Thuy Khanh, Banchenko, Sofia, Paydar, Darius, Leipe, Pia Madeleine, Binting, Lukas, Lauer, Simon, Graziadei, Andrea, Klingen, Robin, Gotthold, Christine, Bürger, Jörg, Bracht, Thilo, Sitek, Barbara, Jan Lebbink, Robert, Malyshkina, Anna, Mielke, Thorsten, Rappsilber, Juri, Spahn, Christian MT, Voigt, Sebastian, Trilling, Mirko, Schwefel, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975947/
https://www.ncbi.nlm.nih.gov/pubmed/36762436
http://dx.doi.org/10.15252/embj.2022112351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975947/
https://www.ncbi.nlm.nih.gov/pubmed/36762436
http://dx.doi.org/10.15252/embj.2022112351

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