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TORC1 phosphorylates and inhibits the ribosome preservation factor Stm1 to activate dormant ribosomes

Target of rapamycin complex 1 (TORC1) promotes biogenesis and inhibits the degradation of ribosomes in response to nutrient availability. To ensure a basal supply of ribosomes, cells are known to preserve a small pool of dormant ribosomes under nutrient‐limited conditions. However, the regulation of...

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Detalles Bibliográficos
Autores principales: Shetty, Sunil, Hofstetter, Jon, Battaglioni, Stefania, Ritz, Danilo, Hall, Michael N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975950/
https://www.ncbi.nlm.nih.gov/pubmed/36691768
http://dx.doi.org/10.15252/embj.2022112344