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Fast and scarless: Prx1(+) fibroblasts turbocharge healing

Our oral cavity has evolved a capacity for rapid healing without scarring. In this issue of JEM, Ko et al. (2022. J. Exp. Med. https://doi.org/10.1084/jem.20221350) identify a Prx1(+) fibroblast progenitor that drives oral regeneration by summoning pro-healing TGFβ1(+) macrophages.

Detalles Bibliográficos
Autores principales: Kratofil, Rachel M., Naik, Shruti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975960/
https://www.ncbi.nlm.nih.gov/pubmed/36745188
http://dx.doi.org/10.1084/jem.20222139
Descripción
Sumario:Our oral cavity has evolved a capacity for rapid healing without scarring. In this issue of JEM, Ko et al. (2022. J. Exp. Med. https://doi.org/10.1084/jem.20221350) identify a Prx1(+) fibroblast progenitor that drives oral regeneration by summoning pro-healing TGFβ1(+) macrophages.