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StarmapVis: An interactive and narrative visualisation tool for single-cell and spatial data

Current single-cell visualisation techniques project high dimensional data into ‘map’ views to identify high-level structures such as cell clusters and trajectories. New tools are needed to allow the transversal through the high dimensionality of single-cell data to explore the single-cell local nei...

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Detalles Bibliográficos
Autores principales: Ma, Shichao, Fang, Xiunan, Yao, Yu, Li, Jianfu, Morgan, Daniel C., Xia, Yongyan, Kwok, Crystal S.M., Lo, Michelle C.K., Siu, Dickson M.D., Tsia, Kevin K., Yang, Andrian, Ho, Joshua W.K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976191/
https://www.ncbi.nlm.nih.gov/pubmed/36874160
http://dx.doi.org/10.1016/j.csbj.2023.02.023
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author Ma, Shichao
Fang, Xiunan
Yao, Yu
Li, Jianfu
Morgan, Daniel C.
Xia, Yongyan
Kwok, Crystal S.M.
Lo, Michelle C.K.
Siu, Dickson M.D.
Tsia, Kevin K.
Yang, Andrian
Ho, Joshua W.K.
author_facet Ma, Shichao
Fang, Xiunan
Yao, Yu
Li, Jianfu
Morgan, Daniel C.
Xia, Yongyan
Kwok, Crystal S.M.
Lo, Michelle C.K.
Siu, Dickson M.D.
Tsia, Kevin K.
Yang, Andrian
Ho, Joshua W.K.
author_sort Ma, Shichao
collection PubMed
description Current single-cell visualisation techniques project high dimensional data into ‘map’ views to identify high-level structures such as cell clusters and trajectories. New tools are needed to allow the transversal through the high dimensionality of single-cell data to explore the single-cell local neighbourhood. StarmapVis is a convenient web application displaying an interactive downstream analysis of single-cell expression or spatial transcriptomic data. The concise user interface is powered by modern web browsers to explore the variety of viewing angles unavailable to 2D media. Interactive scatter plots display clustering information, while the trajectory and cross-comparison among different coordinates are displayed in connectivity networks. Automated animation of camera view is a unique feature of our tool. StarmapVis also offers a useful animated transition between two-dimensional spatial omic data to three-dimensional single cell coordinates. The usability of StarmapVis is demonstrated by four data sets, showcasing its practical usability. StarmapVis is available at: https://holab-hku.github.io/starmapVis.
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spelling pubmed-99761912023-03-02 StarmapVis: An interactive and narrative visualisation tool for single-cell and spatial data Ma, Shichao Fang, Xiunan Yao, Yu Li, Jianfu Morgan, Daniel C. Xia, Yongyan Kwok, Crystal S.M. Lo, Michelle C.K. Siu, Dickson M.D. Tsia, Kevin K. Yang, Andrian Ho, Joshua W.K. Comput Struct Biotechnol J Software/Web server Article Current single-cell visualisation techniques project high dimensional data into ‘map’ views to identify high-level structures such as cell clusters and trajectories. New tools are needed to allow the transversal through the high dimensionality of single-cell data to explore the single-cell local neighbourhood. StarmapVis is a convenient web application displaying an interactive downstream analysis of single-cell expression or spatial transcriptomic data. The concise user interface is powered by modern web browsers to explore the variety of viewing angles unavailable to 2D media. Interactive scatter plots display clustering information, while the trajectory and cross-comparison among different coordinates are displayed in connectivity networks. Automated animation of camera view is a unique feature of our tool. StarmapVis also offers a useful animated transition between two-dimensional spatial omic data to three-dimensional single cell coordinates. The usability of StarmapVis is demonstrated by four data sets, showcasing its practical usability. StarmapVis is available at: https://holab-hku.github.io/starmapVis. Research Network of Computational and Structural Biotechnology 2023-02-14 /pmc/articles/PMC9976191/ /pubmed/36874160 http://dx.doi.org/10.1016/j.csbj.2023.02.023 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Software/Web server Article
Ma, Shichao
Fang, Xiunan
Yao, Yu
Li, Jianfu
Morgan, Daniel C.
Xia, Yongyan
Kwok, Crystal S.M.
Lo, Michelle C.K.
Siu, Dickson M.D.
Tsia, Kevin K.
Yang, Andrian
Ho, Joshua W.K.
StarmapVis: An interactive and narrative visualisation tool for single-cell and spatial data
title StarmapVis: An interactive and narrative visualisation tool for single-cell and spatial data
title_full StarmapVis: An interactive and narrative visualisation tool for single-cell and spatial data
title_fullStr StarmapVis: An interactive and narrative visualisation tool for single-cell and spatial data
title_full_unstemmed StarmapVis: An interactive and narrative visualisation tool for single-cell and spatial data
title_short StarmapVis: An interactive and narrative visualisation tool for single-cell and spatial data
title_sort starmapvis: an interactive and narrative visualisation tool for single-cell and spatial data
topic Software/Web server Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976191/
https://www.ncbi.nlm.nih.gov/pubmed/36874160
http://dx.doi.org/10.1016/j.csbj.2023.02.023
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