DeltaMSI: artificial intelligence-based modeling of microsatellite instability scoring on next-generation sequencing data

BACKGROUND: DNA mismatch repair deficiency (dMMR) testing is crucial for detection of microsatellite unstable (MSI) tumors. MSI is detected by aberrant indel length distributions of microsatellite markers, either by visual inspection of PCR-fragment length profiles or by automated bioinformatic scor...

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Detalles Bibliográficos
Autores principales: Swaerts, Koen, Dedeurwaerdere, Franceska, De Smet, Dieter, De Jaeger, Peter, Martens, Geert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976396/
https://www.ncbi.nlm.nih.gov/pubmed/36859168
http://dx.doi.org/10.1186/s12859-023-05186-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976396/
https://www.ncbi.nlm.nih.gov/pubmed/36859168
http://dx.doi.org/10.1186/s12859-023-05186-3

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