Comparative study of extracellular vesicles derived from mesenchymal stem cells and brain endothelial cells attenuating blood–brain barrier permeability via regulating Caveolin-1-dependent ZO-1 and Claudin-5 endocytosis in acute ischemic stroke

BACKGROUND: Blood–brain barrier (BBB) disruption is a major adverse event after ischemic stroke (IS). Caveolin-1 (Cav-1), a scaffolding protein, played multiple roles in BBB permeability after IS, while the pros and cons of Cav-1 on BBB permeability remain controversial. Numerous studies revealed th...

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Detalles Bibliográficos
Autores principales: Li, Yiyang, Liu, Bowen, Zhao, Tingting, Quan, Xingping, Han, Yan, Cheng, Yaxin, Chen, Yanling, Shen, Xu, Zheng, Ying, Zhao, Yonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976550/
https://www.ncbi.nlm.nih.gov/pubmed/36855156
http://dx.doi.org/10.1186/s12951-023-01828-z

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