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Intestinal SEC16B modulates obesity by regulating chylomicron metabolism

OBJECTIVE: Genome-wide association studies (GWAS) have identified genetic variants in SEC16 homolog B (SEC16B) locus to be associated with obesity and body mass index (BMI) in various populations. SEC16B encodes a scaffold protein located at endoplasmic reticulum (ER) exit sites that is implicated t...

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Detalles Bibliográficos
Autores principales: Shi, Ruicheng, Lu, Wei, Tian, Ye, Wang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976576/
https://www.ncbi.nlm.nih.gov/pubmed/36796587
http://dx.doi.org/10.1016/j.molmet.2023.101693