SPINK6 inhibits human airway serine proteases and restricts influenza virus activation

SPINK6 was identified in human skin as a cellular inhibitor of serine proteases of the KLK family. Airway serine proteases are required to cleave hemagglutinin (HA) of influenza A viruses (IAVs) to initiate an infection in the human airway. We hypothesized that SPINK6 may inhibit common airway serin...

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Detalles Bibliográficos
Autores principales: Wang, Dong, Li, Cun, Chiu, Man Chun, Yu, Yifei, Liu, Xiaojuan, Zhao, Xiaoyu, Huang, Jingjing, Cheng, Zhongshan, Yuan, Shuofeng, Poon, Vincent, Cai, Jian‐Piao, Chu, Hin, Chan, Jasper Fuk‐Woo, To, Kelvin Kai‐Wang, Yuen, Kwok Yung, Zhou, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976594/
https://www.ncbi.nlm.nih.gov/pubmed/34826211
http://dx.doi.org/10.15252/emmm.202114485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976594/
https://www.ncbi.nlm.nih.gov/pubmed/34826211
http://dx.doi.org/10.15252/emmm.202114485

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