Imaging and treatment with (68)Gallium and (177)Lutetium-DOTATATE in a rare SSTR2 and ESWR1-CREM fusion positive undifferentiated round cell tumour of the lung

The authors present a 45-year-old lady with a rare undifferentiated round cell tumour of the lung with a ESWR1-CREM fusion gene that progressed despite multiple lines of therapy. The tumour was Somatostatin Receptors Type 2 (SSTR2) positive and avid on (68)Gallium-DOTATATE imaging. This allowed for...

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Detalles Bibliográficos
Autores principales: Kumaran, Arjunan, Koo, Si Xuan, Yeong, Joe, Takano, Angela Maria, Farid, Mohamad, Loke, Siu Hoong, Nei, Wen Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Institute of Radiology. 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976727/
https://www.ncbi.nlm.nih.gov/pubmed/36873236
http://dx.doi.org/10.1259/bjrcr.20220094
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author Kumaran, Arjunan
Koo, Si Xuan
Yeong, Joe
Takano, Angela Maria
Farid, Mohamad
Loke, Siu Hoong
Nei, Wen Long
author_facet Kumaran, Arjunan
Koo, Si Xuan
Yeong, Joe
Takano, Angela Maria
Farid, Mohamad
Loke, Siu Hoong
Nei, Wen Long
author_sort Kumaran, Arjunan
collection PubMed
description The authors present a 45-year-old lady with a rare undifferentiated round cell tumour of the lung with a ESWR1-CREM fusion gene that progressed despite multiple lines of therapy. The tumour was Somatostatin Receptors Type 2 (SSTR2) positive and avid on (68)Gallium-DOTATATE imaging. This allowed for novel treatment with Peptide Receptor Radionuclide Therapy (PRRT) using (177)Lutetium-DOTATATE after all other standard of care options were exhausted.
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spelling pubmed-99767272023-03-02 Imaging and treatment with (68)Gallium and (177)Lutetium-DOTATATE in a rare SSTR2 and ESWR1-CREM fusion positive undifferentiated round cell tumour of the lung Kumaran, Arjunan Koo, Si Xuan Yeong, Joe Takano, Angela Maria Farid, Mohamad Loke, Siu Hoong Nei, Wen Long BJR Case Rep Case Report The authors present a 45-year-old lady with a rare undifferentiated round cell tumour of the lung with a ESWR1-CREM fusion gene that progressed despite multiple lines of therapy. The tumour was Somatostatin Receptors Type 2 (SSTR2) positive and avid on (68)Gallium-DOTATATE imaging. This allowed for novel treatment with Peptide Receptor Radionuclide Therapy (PRRT) using (177)Lutetium-DOTATATE after all other standard of care options were exhausted. The British Institute of Radiology. 2022-11-08 /pmc/articles/PMC9976727/ /pubmed/36873236 http://dx.doi.org/10.1259/bjrcr.20220094 Text en © 2022 The Authors. Published by the British Institute of Radiology https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
spellingShingle Case Report
Kumaran, Arjunan
Koo, Si Xuan
Yeong, Joe
Takano, Angela Maria
Farid, Mohamad
Loke, Siu Hoong
Nei, Wen Long
Imaging and treatment with (68)Gallium and (177)Lutetium-DOTATATE in a rare SSTR2 and ESWR1-CREM fusion positive undifferentiated round cell tumour of the lung
title Imaging and treatment with (68)Gallium and (177)Lutetium-DOTATATE in a rare SSTR2 and ESWR1-CREM fusion positive undifferentiated round cell tumour of the lung
title_full Imaging and treatment with (68)Gallium and (177)Lutetium-DOTATATE in a rare SSTR2 and ESWR1-CREM fusion positive undifferentiated round cell tumour of the lung
title_fullStr Imaging and treatment with (68)Gallium and (177)Lutetium-DOTATATE in a rare SSTR2 and ESWR1-CREM fusion positive undifferentiated round cell tumour of the lung
title_full_unstemmed Imaging and treatment with (68)Gallium and (177)Lutetium-DOTATATE in a rare SSTR2 and ESWR1-CREM fusion positive undifferentiated round cell tumour of the lung
title_short Imaging and treatment with (68)Gallium and (177)Lutetium-DOTATATE in a rare SSTR2 and ESWR1-CREM fusion positive undifferentiated round cell tumour of the lung
title_sort imaging and treatment with (68)gallium and (177)lutetium-dotatate in a rare sstr2 and eswr1-crem fusion positive undifferentiated round cell tumour of the lung
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976727/
https://www.ncbi.nlm.nih.gov/pubmed/36873236
http://dx.doi.org/10.1259/bjrcr.20220094
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