CRISPR-Cas9 recognition of enzymatically synthesized base-modified nucleic acids

An enzymatic method has been successfully established enabling the generation of partially base-modified RNA (previously named RZA) constructs, in which all G residues were replaced by isomorphic fluorescent thienoguanosine ((th)G) analogs, as well as fully modified RZA featuring (th)G, 5-bromocytos...

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Detalles Bibliográficos
Autores principales: Yang, Hui, Eremeeva, Elena, Abramov, Mikhail, Jacquemyn, Maarten, Groaz, Elisabetta, Daelemans, Dirk, Herdewijn, Piet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976875/
https://www.ncbi.nlm.nih.gov/pubmed/36611237
http://dx.doi.org/10.1093/nar/gkac1147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976875/
https://www.ncbi.nlm.nih.gov/pubmed/36611237
http://dx.doi.org/10.1093/nar/gkac1147

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