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CRISPR-Cas9 recognition of enzymatically synthesized base-modified nucleic acids
An enzymatic method has been successfully established enabling the generation of partially base-modified RNA (previously named RZA) constructs, in which all G residues were replaced by isomorphic fluorescent thienoguanosine ((th)G) analogs, as well as fully modified RZA featuring (th)G, 5-bromocytos...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976875/ https://www.ncbi.nlm.nih.gov/pubmed/36611237 http://dx.doi.org/10.1093/nar/gkac1147 |