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Men who inject opioids exhibit altered tRNA-Gly-GCC isoforms in semen
In addition to their role in protein translation, tRNAs can be cleaved into shorter, biologically active fragments called tRNA fragments (tRFs). Specific tRFs from spermatocytes can propagate metabolic disorders in second generations of mice. Thus, tRFs in germline cells are a mechanism of epigeneti...
Autores principales: | Gornalusse, Germán, Spengler, Ryan M, Sandford, Erin, Kim, Yeseul, Levy, Claire, Tewari, Muneesh, Hladik, Florian, Vojtech, Lucia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976897/ https://www.ncbi.nlm.nih.gov/pubmed/36661332 http://dx.doi.org/10.1093/molehr/gaad003 |
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