Interaction of human HelQ with DNA polymerase delta halts DNA synthesis and stimulates DNA single-strand annealing

DNA strand breaks are repaired by DNA synthesis from an exposed DNA end paired with a homologous DNA template. DNA polymerase delta (Pol δ) catalyses DNA synthesis in multiple eukaryotic DNA break repair pathways but triggers genome instability unless its activity is restrained. We show that human H...

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Detalles Bibliográficos
Autores principales: He, Liu, Lever, Rebecca, Cubbon, Andrew, Tehseen, Muhammad, Jenkins, Tabitha, Nottingham, Alice O, Horton, Anya, Betts, Hannah, Fisher, Martin, Hamdan, Samir M, Soultanas, Panos, Bolt, Edward L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976902/
https://www.ncbi.nlm.nih.gov/pubmed/36718939
http://dx.doi.org/10.1093/nar/gkad032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9976902/
https://www.ncbi.nlm.nih.gov/pubmed/36718939
http://dx.doi.org/10.1093/nar/gkad032

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